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ISSN : 1225-0082(Print)
ISSN : 2288-1905(Online)
The Medical Journal of Chosun University Vol.38 No.1 pp.49-53

비호지킨 림프종 완치 후 발생한 호지킨 림프종 1예

이희정*, 김형호, 서준원, 박현정, 박상곤
조선대학교 의과대학 내과, 종양혈액내과

A Case of Sequential Hodgkin’s Lymphoma following Successful Treatment of Non-Hodgkin’s Lymphoma

Hee-Jeong Lee*, Hyung-Ho Kim, Jun-Won Seo, Hyun-Jung Park, Sang-Gon Park
Department of Internal Medicine, Hemato-oncology, Chosun University Hospital
(Received March 4, 2013; Accepted March 15, 2013)


Development of two different histologic types of lymphoma in the same person is rare. Sequential lymphoma is defined astwo different types of lymphoma occurring sequentially in the same person. In particular, sequential Hodgkin’s lymphoma(HL) following non-Hodgkin’s lymphoma (NHL) is extremely rare. A 63-year-old female diagnosed with B-cell NHL at themass in T3 received treatment with an R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone)protocol for six cycles. However, 12 months later, the patient complained of a left neck mass and excisional biopsy was performed.Microscopically the biopsied tissue showed Reed-Stemberg cells and confirmed the diagnosis of HL. The patientwas treated with ABVD (adriamycin, bleomycin, vinblastine and dacarbazine) for four cycles. Although the possibility of asecondary malignancy cannot be excluded, this is a rare case of sequential Hodgkin’s lymphoma following Non-Hodgkin’slymphoma.


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