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ISSN : 1225-0082(Print)
ISSN : 2288-1905(Online)
The Medical Journal of Chosun University Vol.44 No.1 pp.62-65

Neoadjuvant imatinib mesylate for debulking therapy of rectal gastrointestinal stromal tumor

Jun Hyung Lee,Jun Lee,Seong Jung Kim
Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, Korea
Corresponding author Jun Lee Department of Internal Medicine, College of Medicine, Chosun University, 365 Pilmun-daero, Dong-gu, Gwangju 61453, Korea Tel: +82-62-220-3012 Fax: +82-62-224-5494


Gastrointestinal stromal tumor (GIST) is the most common soft tissue sarcoma of the gastrointestinal tract. Surgery is the primary treatment of choice for patients with localized or potentially resectable GIST, whereas imatinib is the main treatment for patients with advanced, unresectable, or metastatic GIST. Neoadjuvant treatment with imatinib is not routinely recommended unless there is significant justification for reducing the tumor size in order to improve surgical outcome. The authors describe a case of a 48-year-old man who confirmed huge rectal GIST, and received successful neoadjuvant treatment with imatinib for preserving anal sphincter function followed by transanal excision.

직장에 발생한 위장관간질종양의 감량치료를 위한 Imanitib 선행치료

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